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mavorixafor will boost the stage or outcome of codeine by affecting hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a powerful CYP2D6 inhibitor) is contraindicated with medication which are very depending on CYP2D6 for clearance.benzhydrocodone/acetaminophen and codeine each boost sedation. Stay clear of or Use Alternate Drug. Limit